************ Requirements ************ A list of features to be added to the package. Requirements marked with ``(*)`` are not yet assigned a version number. [R01] ``bam-filter`` covered with tests [R02] ``samtools`` replaced by ``pysam`` [R03] Add option ``--partition`` to ``sm-analysis`` to select what fraction of an input file must be processed [R04] Implement new ``csv`` output with methilation state per molecule and circular consensus DNA sequence [R05] Option to select model in ``sm-analysis`` (simply providing a string, eg ``P6-C4``). Instead of crashing if the expected model dows not agree with the chemistry, the program looks for different models in the directory and tests them in turn until a valid one is found. [R06] *Legacy code* covered with tests: minimal ``sm-analysis`` functionality [R07] Optimization: Reduce the number of temporary files that are created by ``sm-analysis``. [R08] Decouple from ipdSummary using kineticsTools as a package [R09] Automatically identify structure of BAM file: * where the molecule id is located (column) [R10] BAM files created contain info about source file and modifications introduced. [R11] Miscelaneous improvements: * protection against tracebacks (they should not be presented to end user) * version * debugging [R12] Path to external tools can be provided: * ``blasr`` * ``pbindex`` * ``ipdSummary`` [R13] Number of processes used by external tools can be chosen. [R14] Resume interrupted ``sm-analysis`` runs. [R15] Various minor input options: * modification types * keep temporary directory? * only produce methylation report * ccs file * aligned ccs file [R16] ``(*)`` Transparent usage of clusters. [R17] GUI [R18] Easy installation [R19] Methylation state conforms to version 2 (see :ref:`methylation-report-format`). [R20] Documentation (I) * Structure documentation * Add quick start and some more docs for end users * add docstrings as a starting point for docs for developers * integrate with sphinx [R21] Methylation report format V3 [R22] Summary doc for humans (html?, pdf?) with: * plots * basic statistics about subreads, molecules, methylations, etc. [R23] New option that disables the standard filters before running the Single Molecule Analysis (``sm-analysis``) [R24] Path to ``ccs`` can be provided as CLO. [R25] Documentation (II) * local distribution and installation of docs * launch local docs in browser [R26] BamFile implementation using pure python library ``pybam`` (or a python3 compliant fork of it) [R27] Organization of files produced by ``sm-analysis``: * log files go to a dedicated ``log/`` directory (each molecule must have its onw log file) * auxiliary files (``ì-shifted...``, aligned BAMs, CCS, etc) must go into a dedicated directory (``aux/``?) [R28] Browsable HTML document with information about status of individual GATCs and the neighbours. [R29] Automatic merge of partition results [R30] Option to choose the window of the reference to be processed by ``ipdSummary``. [R31] Switching to use the ``pbmm2`` aligner by default.